GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs6087771 | 1 | rs6060857 | chr20:30300222 | COX4I2 | chr20:30225691-30232800:+ | 0.12 | 3.87 | 0.000124 | Subcortical brain region volumes |
| THCA | cis | rs6087771 | 1 | rs6060915 | chr20:30330306 | COX4I2 | chr20:30225691-30232800:+ | 0.12 | 3.82 | 0.000154 | Subcortical brain region volumes |
| THCA | cis | rs6087771 | 1 | rs6060919 | chr20:30331922 | COX4I2 | chr20:30225691-30232800:+ | 0.12 | 4.03 | 6.5E-5 | Subcortical brain region volumes |
| THCA | cis | rs6087771 | 1 | rs6060922 | chr20:30333909 | COX4I2 | chr20:30225691-30232800:+ | 0.12 | 4.03 | 6.5E-5 | Subcortical brain region volumes |
| THCA | cis | rs6087771 | 1 | rs6060932 | chr20:30350545 | COX4I2 | chr20:30225691-30232800:+ | 0.12 | 4.03 | 6.51E-5 | Subcortical brain region volumes |
| THCA | cis | rs6087771 | 1 | rs6060933 | chr20:30351903 | COX4I2 | chr20:30225691-30232800:+ | 0.12 | 3.93 | 9.69E-5 | Subcortical brain region volumes |
| THCA | cis | rs6087771 | 1 | rs6060944 | chr20:30372114 | COX4I2 | chr20:30225691-30232800:+ | 0.12 | 4.03 | 6.51E-5 | Subcortical brain region volumes |
| THCA | cis | rs6087771 | 1 | rs6060950 | chr20:30378031 | COX4I2 | chr20:30225691-30232800:+ | 0.12 | 4.05 | 5.97E-5 | Subcortical brain region volumes |
| THCA | cis | rs6087771 | 1 | rs6060962 | chr20:30397847 | COX4I2 | chr20:30225691-30232800:+ | 0.12 | 3.94 | 9.25E-5 | Subcortical brain region volumes |
| THCA | cis | rs7838490 | 1 | rs60622165 | chr8:89599455 | MMP16 | chr8:89049462-89339717:- | 0.16 | 3.65 | 0.000292 | Body mass index and cholesterol (psychopharmacological treatment) |
| THCA | cis | rs1449984 | 1 | rs60628766 | chr2:23423269 | FKBP1B | chr2:24272584-24286548:+ | 0.18 | 3.41 | 0.000715 | Depression (quantitative trait) |
| THCA | cis | rs6012564 | 1 | rs6063352 | chr20:47718594 | ARFGEF2 | chr20:47538275-47653229:+ | -0.13 | -4.12 | 4.47E-5 | Anger |
| THCA | cis | rs6012564 | 1 | rs6063352 | chr20:47718594 | CSE1L | chr20:47662838-47713484:+ | 0.41 | 10.23 | 2.31E-22 | Anger |
| THCA | cis | rs6012564 | 1 | rs6063353 | chr20:47719810 | ARFGEF2 | chr20:47538275-47653229:+ | -0.13 | -4.12 | 4.47E-5 | Anger |
| THCA | cis | rs6012564 | 1 | rs6063353 | chr20:47719810 | CSE1L | chr20:47662838-47713484:+ | 0.41 | 10.23 | 2.31E-22 | Anger |